

…
However, he continued to say that raw execution speed was “not a significant factor” for many applications. “Even if you double the execution speed of something that is 10% of your overall request cost, that is only a 5% overall improvement. If on every request you are hitting memcache/postgresql/mysql 10 times and spending a lot of time in system calls, don’t expect miracles from HipHop.”
Rasmus Lerdorf
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Any doubts about?